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Racehorse poo analysis predicts future success


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21 hours ago
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Victoria Gill
Science correspondent@vic_gill
Kate Stephens
Senior science producer
BBC News  A young racehorse in trainingBBC News
 
The team of veterinary scientists worked with five stud farms for the study into gut microbes and their impact on long-term health

The future success of a racehorse can be detected in the animal’s gut when it is just one month old, research suggests.

A recent veterinary study analysed horses' poo, measuring the bacteria in the digestive systems of more than 50 thoroughbred foals over the first three years of their lives.

The study found the more types of gut microbes a foal had at just four weeks old directly correlates to its future health, and its success on the racecourse.

The findings, published in the journal Scientific Reports, add to an emerging biological picture regarding the importance of the trillions of microbes that live inside young animals’ digestive systems - and their role in long-term health.

BBC News A thoroughbred mare and foalBBC News
 
Like human infants, young horses pick up vital gut bacteria from their mothers and from the environment

“Gut health is absolutely critical,” said lead researcher Chris Proudman, a professor of clinical veterinary science at the University of Surrey.

“There is a growing understanding that what happens in human guts and in animal guts – horses, in this case - has a profound influence on many aspects of health and disease.”

“It’s also about timing,” he explained. “The nature of the gut bacteria in those first few weeks of life predicts the future health, and the future performance, of these horses.”

Young racehorses provide veterinary scientists with an ideal opportunity for studying the gut.

Breeders and trainers of thoroughbred foals typically keep highly detailed records of each animal’s birth, diet and health, as well as any veterinary care they receive.

“Anything we can investigate – to help them be in as good shape as possible – is a really good opportunity for us,” said Jane Black, co-owner of Chasemore stud farm in Surrey, which bred some of the foals involved in the research.

 
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Over the course of three years, owners and trainers recorded how their horses performed on the racecourse, including where they placed and how much prize money they earned.

Meanwhile, scientists regularly collected faecal samples - by collecting horse poo from the stables - from each of the 52 young horses involved in the study.

Researchers were then able to “DNA fingerprint” the samples, providing a regular read-out of the bacteria inside each animal's gut.

Victoria Gill  A young foal in a stableVictoria Gill
 
What is happening in the gut of a foal at four weeks old is critical to its health as an adult

“We can see the amount of bacteria present and identify the different types,” explained Prof Proudman.

“Then we compared that with our health data, and with our racing performance data.”

The study concluded that the more diverse the gut bacteria in a four-week-old foal, the fewer health problems - particularly respiratory diseases - the horse suffered in later life.

Researchers also found a direct relationship between the number of different types of gut bacteria in a month-old foal and its performance on the racecourse when it was older.

Impact of antibiotics

The team of scientists also investigated the long-term consequences of young foals being treated with antibiotics.

Foals treated with antibiotic drugs had fewer types of bacteria in their guts, and subsequently went on to win less prize money in their racing careers compared to horses that had not received early antibiotic treatment.

Prof Proudman said the discovery raised questions about the use of antibiotics, both in animals and in humans, in early life.

“We need to think about things that happen in those first few weeks of life - to make sure that animals and humans' gut bacteria are in a good state at that stage.

"That appears to set them up for a healthy life in the future,” he said.

Professor Roberto La Ragione, also at the University of Surrey, said:  “The next part of our study will examine how we can minimise disruption of gut bacteria when antibiotics have to be used to treat infections [early on].”

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1 hour ago, Murray Fish said:

thankfully paid walled...

Basically they are taking poop from people who have healthy gut biome's and deflavouring/de-smelling it and putting it into gel capsules to deliver good bacteria to the gut.

Two Australians discovered (1982 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1246068/) that a type of bacteria Heliobacter pylori was the main cause of stomach ulcers and stomach cancer in humans.  It also affects horse.

I suffered for a very long time from gastric reflux to the point where I couldn't sleep at night and would end up vomitting.  I'd been treated with Losec and Omaperazole for a long time but they didn't really work.  Before the problem started I used to love a whiskey - but then a sip and I would have really bad "heart burn".  Fortunately I changed Doctors and explained the problem.  She said she knew exactly what the problem was and got me to do a poo test.

I came back positive for Heliobacter pylori - fortunately there is a fix which requires treatment with three different anti-biotics and lays you really low for two weeks.  I'd never watched Games Of Thrones before and was lucky that there was a Box Set on Sky - binged it!

Anyway fixed the problem.  Boy did I enjoy that aged single malt whiskey!!

The two Australians won the Nobel Prize in 2005.  What I've found since is that many Doctors haven't heard of the problem and their first call is prescribing proton inhibitors such as Losec or similar.

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