Thoughts for AGM

[Four shaw]

14 minutes ago, Cockyaleg said:

Bahahaha, charge admitted, but it wasn't me! Remember you brought this here. 

As far back as 2013 there were robust discussions regarding the use of sythesised dermorphin in racing. There are many more examples. 

https://www.paulickreport.com/news/ray-s-paddock/chasing-the-frog-keeping-up-with-slippery-cheaters/

2012
https://www.nytimes.com/2012/06/20/sports/horse-racing-discovers-new-drug-problem-one-linked-to-frogs.html

2015
https://www.horsetalk.co.nz/2015/11/10/new-synthetic-opioid-drug-racehorses-in-new-york/

2017
http://veterinarynews.dvm360.com/veterinarian-charged-with-plot-drug-horses-races

LOL ? far out frog juice is every we’re ....positives aplenty,who would have excess close to home ,maybe the rumours are TRUE and you got bad advice ?.?.?

[Cockyaleg]

Mr Turakina.

I did say at the outset that you should leave well alone. In my view you were treated leniently to a charge you admitted. That should have been the end of it, but as you brought this here, not me, you opened the conversation up to the world. 

There is no hate in my posts, just a quest for the truth. However, I have no respect for anyone who casts apersions on their fellow participants, and you did just that when you used kennel block nobbling as a possible excuse for your positives. Pointing the finger at others in order to cast doubt on your guilt is appalling behaviour. You did not point to any person or persons that could be responsible or offer evidence of possible intent, just deflected.

Dermorphin is a long lasting pain killer that allows and animal to run/run harder by blocking the pain receptors. No pain, no lame. It can also put an animal into a euphoric state which at the right dosage could be beneficial when looking to continue running an animal carrying injury. You don't need a science degree to work out why someone would use it.

The lab tests came back positive to synthetic dermorpin, not natural, synthetic. The difference between the two is there chemical signature. That's how scientists are able to differentiate in forensic labs. Your theory that we have mammals in New Zealand producing synthetic forms of morphine is insane. I am yet to see  anyone smoke or shoot up a possum. I suggest you publish your theory and have the scientific community critique it. You have the only greyhounds in New Zealand who possess this ability to synthesise dermorphin, and in the last five years there have been more than 20,000 drug tests returned. You claim there have been very few dermorphin positives, I suggest you work on your research skills.

Quote from your opening post, "I have to be the dumbest guy in racing in all 3 codes not just in NZ but the whole world." On that we both agree. On a positive note "Plattapie', catchy name. Could be a new venture to consider. Good luck to you and your family, and that was sincere.

[Yankiwi]

1 hour ago, Cockyaleg said:

 In my view you were treated leniently to a charge you admitted. 

I concur.

For someone to "more likely than not" have administered their dogs with SYNTEHIC Dermorpin on at least 4 occasions, the consequences are extremely lenient. That's a greyhound matter, so therefore it has no direct implications upon my life.

What I believe you have done which does have direct implications upon my life, is to be collecting a benefit which my tax dollars are contributing towards while also being a professional Greyhound trainer. 

 

Thus far in the 2018/2019 season GRNZ has this about your earnings.

 

The 2017/2018 season shows this.

 

That's nearly $120K in earnings over the last two years. That amount is substantially more than I've earned over the same period working for an employer 40 hours a week.

So why are my tax dollars being used to support you?

[My Name Is]

Good Morning All,

Thank you Four Shaw, If I got bad advice about dermophin, your common sense would be to stop after the first two.But im  that dumb.

Thank you Cockyaleg, Not sure what your question is, But you rite very well. Since this did not happen at my place, As all my dogs have been locked in their kennels with video surveillance since the beginning of the year .The only place the dog was out of my care was in the Wanganui kennel block.So it must have been there. Thats if you think someone injected my dog?  How long have they been testing for dermophin ? Five years is it ?

I dont think my dogs have been injected with dermorphin, but they have it in there gut bacteria.

 

Dermorphin Production by Bacteria
 Distinct pathways for modification of the bacterial cell wall by non-canonical D-amino acids
Non canonical amino acids are amino acids that are not one of the 20 amino acids normally found in structural proteins in animals.
L,D-transpeptidases incorporate non-canonical D-amino acids into tetrapeptides of V. cholerae PG.
The difference between efficiencies for the forward (D-Ala → D-Met) and reverse (D-Met → D-Ala) reactions suggests that accumulation of D-Met muropeptides would be favoured in vivo, even if both D-Met and D-Ala were simultaneously present at similar concentrations. Therefore, in stationary phase, when D-Met is present, LdtA is likely to promote accumulation of muro4M peptides, rather than a continual exchange of the C-terminal amino acid within tetrapeptides.
Muro4 peptides are tetrapeptides used in the formation of bacterial cell walls.
In natural environments, bacterial communities typically contain multiple species (Straight and Kolter, 2009), which could produce a variety of D-amino acids (Lam et al, 2009)
The D-amino acid in Dermorphin is D-Arginine which according to the above article could possibly be produced by naturally occurring bacterial communities, eg, in the intestine.

Different processes control formation of D-Met muropeptides in bacteria
To begin to explore whether the pathways for incorporation of NCDAAs are conserved, we assessed whether D-Met was targeted to equivalent muropeptides within diverse species, and whether mutations and antibiotics have uniform effects upon D-Met incorporation. Unexpectedly, these assays revealed that only V. cholerae and C. crescentus incorporate NCDAAs into both tetrapeptides and pentapeptides, although C. crescentus, unlike V. cholerae, contains predominantly muro5M (Figure 4D; Supplementary Figure S1). PG from all other organisms tested contained just one of the two classes of peptides. Following growth in media supplemented with D-Met, muro4M peptides were detected in PG from E. coli and P. aeruginosa, while muro5M peptides were detected in PG from B. subtilis, E. faecalis and S. aureus (Figure 4D; 
E.coli is a naturally occuring bacteria in mammalian intestines.
NCDAAs, such as D-Met, are incorporated at two distinct sites within V. cholerae PG subunits. The majority of D-Met (80%) is present as the C-terminal amino acid within monomeric or dimeric tetramers (muro4M), while the remainder comprises the C-terminal amino acid within pentapeptides (muro5M). Formation of muro4M peptides is dependent upon Ldts, inner membrane-anchored periplasmic proteins that catalyse L,D crosslinking of muropeptides and linkage of lipoprotein Lpp to PG (Magnet et al, 2007b,
In vitro characterization of a purified Ldt from V. cholerae (LdtA) revealed that it can exchange the C-terminal amino acid of a variety of tetrapeptide substrates. However, LdtA is more efficient at catalysing exchange in dimeric than in monomeric substrates, and it more readily catalyses replacement of D-Ala by D-Met than the reverse reaction. The latter finding indicates that LdtA should promote muro4M accumulation in stationary phase, when NCDAAs are produced. LdtA can accept many D-amino acids as substrates, a flexibility that may enable reaction to the range of D-amino acids produced during stationary phase by diverse organisms in the natural environment.
Tetrapeptide formation incorporating D-amino acids can occur naturally with a variety of tetrapeptides able to be formed.
Peptidoglycan is a polysaccharide made of two glucose derivatives, N-acetylglucosamine (NAG) and N-acetylmuramic acid (NAM), alternated in long chains. The chains are cross-linked to one another by a tetrapeptide that extends off the NAM sugar unit, allowing a lattice-like structure to form. The four amino acids that compose the tetrapeptide are: L-alanine, D-glutamine, L-lysine or meso-diaminopimelic acid (DPA), and D-alanine. Typically only the L-isomeric form of amino acids are utilized by cells but the use of the mirror image D-amino acids provides protection from proteases that might compromise the integrity of the cell wall by attacking the peptidoglycan. The tetrapeptides can be directly cross-linked to one another, with the D-alanine on one tetrapeptide binding to the L-lysine/ DPA on another tetrapeptide.
Tetrapeptides are naturally produced in large quantities for bacterial cell wall production with D-amino acids typically incorporated .
 
Octapeptides synthesized from D amino acids were absorbed from the intestine and excreted in urine of normal rats drinking 5% glucose/1% creatinine containing the 125I-labeled peptides at 0.1-25 mg/dl
Octapeptides being considerably larger and more complex than tetrapeptides, it is reasonable to assume that tetrapeptides would also be absorbed from the mammalian intestine. 
   The main structural features of the cell wall peptidoglycan of E.coli B have been established by Weidel and co-workers. According to these authors the principal repeating unit in this peptidoglycan is represented by the disaccharide tetrapeptide GNAc-MurNAc-L-Ala-D-Glu-meso-DAP-D-Ala.   
Tetrapeptides being an integral part of bacterial cell walls would naturally be released into the intestine upon death and breakdown  of the bacteria. Absorption of some of these breakdown products is entirely logical.
                         
Preprodermaseptin b and preproadenoregulin have considerable sequence identities to the precursors encoding the opioid heptapeptides dermorphin, dermenkephalin, and deltorphins
The hyperdivergence of modern antimicrobial peptides and the number of peptides per species result from repeated duplications of an approximately 150-million-year-old ancestral gene and accelerated mutations of the mature peptide domain, probably involving a mutagenic, error-prone, DNA polymerase similar to Escherichia coli Pol V.
Although many of the peptides produced by frogs are antibacterial, they are produced by a similar gene in E.coli which has the ability to produce a variety of tetrapeptides.
No work appears to have been on whether E.coli or other intestinal bacteria can produce the tetrapeptide sequence for dermorphin but it seems entirely logical that this is possible.
Dermorphin is not found in humans or other mammals and similar D-amino acid peptides have only been found in bacteria, amphibians and molluscs.[5] Dermorphin appears to be made in these through an unusual posttranslational modification carried out by an amino acid isomerase.[6] This unusual process is needed because the D-alanine in this peptide is not among the 20 amino acids coded for in the genetic code and thus the peptide cannot be synthesized in the usual way from the encodings in the genome of an organism.
An isomerase is a specific enzyme capable of transforming an L-Amino acid into a D-Amino acid.  

Thank you Yankiwi, 

"What I believe you have done which does have direct implications upon my life, is to be collecting a benefit which my tax dollars are contributing towards while also being a professional Greyhound trainer. "

Please Apologise as Im not a professional greyhound trainer and I have have no direct impact on you or any other tax payers life.Hold it, Im a tax payer, so apart from me.

I am a hobbyist with a life time of experience ,and that's why with my family's help we do greyhounds.

"That's nearly $120K in earnings over the last two years. That amount is substantially more than I've earned over the same period working for an employer 40 hours a week."

With family help, Im 7 days a week with no guarantee of making any dollars. The year before was 12k, you did earn more than that i hope,and in 2014/15 it was 4k.

Yes I was doing very well thank you, Makes you think WHY would I do what you are saying I have done? 

Please start another thread on The unemployed, sickness bennys,(pensioners ?)taking all your tax dollars, that are in NZ racing.

As this subject is not about dermorphin.

Thank you, 

 

 

 

[Four shaw]

Yep bad advice.....cunning more like......u played a sharp opening hand ,threw the 2nd......went all in on the 3rd before the big time bluff.U say bacteria the cause yet ya gave two of the positive dogs to other trainers, so ya don,t believe it is gonna happen again. Big time joke.

[Yankiwi]

I can fully understand how my last question has hit a nerve & you've asked me to get back on subject.

If I was putting it to the system, I wouldn't feel comfortable taking about it on a forum.

 

Now, back to that subject.

 

On ‎6‎/‎07‎/‎2019 at 9:22 AM, My Name Is said:

How can you get it (No you can not just add it to cart)?

 

Maybe I can help you with one of your initial questions.

https://www.medchemexpress.com/Dermorphin.html

https://www.genwaybio.com/dermorphin

https://www.abbiotec.com/peptides/dermorphin-peptide

https://www.mybiosource.com/peptide/dermorphin/658078

 

And to top this list off (as there are too many to list options I've found to add it to my cart)

https://www.alibaba.com/showroom/dermorphin.html

I've purchased heaps of things from Aliexpress, owned by Alibaba over the last couple of years... However, my account history would clearly show I've never purchased Dermorphin.

[Yankiwi]

3 hours ago, My Name Is said:

Please Apologise as Im not a professional greyhound trainer and I have have no direct impact on you or any other tax payers life.Hold it, Im a tax payer, so apart from me.

As for apologising, don't expect one from me.

A professional make money for his time & effort.

A hobbyist does not create monetary earning for their time & effort.

[Cockyaleg]

6 hours ago, My Name Is said:

Good Morning All,

I dont think my dogs have been injected with dermorphin, but they have it in there gut bacteria.

 

 

 

 

 

 

In my chosen field, the ability to communicate to a reasonable level in both spoken and written language is a prerequisite. Is it not the same for your industry?

Thank you for providing that opinion. I am assuming it was written by Dr, Jansen, retired vet. It would have been helpful to read the actual article that Dr. Jansen based his opinion on. To know when the reference material was written, by whom, and date that it was published, if published at all. It would also have been helpful to include any peer reviews that followed publishing. What you have presented is in no way proof of innocence. What you have provided is an opinion only.

The point I would like to make about theory is, it is unproven conjecture, a hypothesis. And this piece says it is exactly that, it uses words like reasonable to assume, possibly, unusual posttranslational modification, etc. Now the second point I would like to touch on is the failure rate of clinical trials to field trials. What can be produced in a controlled environment, under controlled conditions cannot always be duplicated outside the lab. The judiciary quite rightly discarded the theory as there exists no probability in fact. The hypothesis may never be tested, the hypothesis may fail, a declaration of innocence cannot be based on the possibility of something that may never happen.

JCA " [22] While Dr. Jansen’s view does raise some interesting conclusions, there is simply a lack of an evidential basis, or research, to support a conclusion which could be defined as a hypothesis at this stage. We also note that Mr. Duganzich, while offering up some potential views on how the Dermorphin could have made its way into NIGHT HOWLER’s system, has provided no specific evidence to advance that further."

On the subject of the WGRC kennel block cameras.

JCA "[23] It is clear that that RIU are alleging presentation rather than administration, so there is no suggestion of any intentional involvement on the part of the Respondent. What we must consider is whether Mr. Duganzich presented the dog to race with the substance in its system. The only other alternative suggested by him is that an intentional administration occurred in the kennelling block at Whanganui. In our assessment, there is simply no strong evidence to rely on that. While the CCTV surveillance system at the track may be dated, that alone is not a sufficient factor to support that view."

It has been brought to my attention that both your mother and father have been WGRC board members at various times. The informant also stated that your mother was a board member while the present camera system was in operation. Only now these cameras have become an issue for you and your family? You wrote today: 

"I dont think my dogs have been injected with dermorphin, but they have it in there gut bacteria."

That statement contradicts your father's hearing statement below: 
JCA "[12] Lay Advocate. His understanding was that it had to also be injected in order for it to be present in the animal’s system."

You did not challenge any of the evidence presented by the RIU.

JCA "[7] The RIU had also circulated as part of Disclosure, four Briefs of Evidence. These were from Mr. Malcolm Wall, Dr. David Palmer, Mr. Simon Irving, and Dr. Malcolm Jansen. Mr. Duganzich stated that he had no issue(s) with the Briefs, and did not wish to challenge their contents."

In conclusion. You offered no evidence at all. The penalty is no penalty at all. You have no dogs and stated you were leaving the industry. The suspension means nothing. If you used your beneficiary status to diminish any possible fine, it worked. If that staus was falsly declared, that would open up a whole new can of worms.
 

[gambler]

Cock ya leg. Spot on. Andy, Bev, Earl you disgusting pack cheats

[Cockyaleg]

5 hours ago, Four shaw said:

Yep bad advice.....cunning more like......u played a sharp opening hand ,threw the 2nd......went all in on the 3rd before the big time bluff.U say bacteria the cause yet ya gave two of the positive dogs to other trainers, so ya don,t believe it is gonna happen again. Big time joke.

Four Shaw, well spotted Sir!            Mr. Turakina made the following statement earlier today:

"I dont think my dogs have been injected with dermorphin, but they have it in there gut bacteria."

Well spotted indeed. Beggers belief! They have it in there gut bacteria, yet what does he do? Only gives two of the positive dogs to other trainers. Tuna Speed to M Gowan. Night Howler to L Doody. Do they know the dogs have it in there gut bacteria? So based on your own statement, both dogs could return a positive with the new trainers. You Mr. Turakina are either an arsehole or a BIGTIME LIAR!

[Mehe]

Lol when one of the dogs won it had never lead out this time it did 

The second dog has got very quick first sections 

I said to someone that day that dog was on something and I was so right 

So the dog must have been off the property or injected on the property 

Earl your saying your property has security cameras on it have you checked them or had someone else check them  

[My Name Is]

Thanks you, Gambler, Once again,I Might be disgusting but am not a cheat.

Thanks Mehe, Yes the cameras were checked. 

Thank you Yankiwi, All info on this drug can only help.

Thank you Cockyaleg, You are a school teacher and communicate very well,Im a 4th form drop out, who talks more to dogs than people.Thanks for your kind words for my family ,and Tina says high,or was it why?

In conclusion. You offered no evidence at all. The penalty is no penalty at all. You have no dogs and stated you were leaving the industry. The suspension means nothing. If you used your beneficiary status to diminish any possible fine, it worked. If that staus was falsly declared, that would open up a whole new can of worms.

Not really a question,But In conclusion I have never herd of this drug before the knock on the door ,and you,the JCA and RIU want me to defend how this has happen,when I have no idea. The penalty is reflective of my copablity. I had to give away all my dogs,we breed and raced,That in its self is more heart wrenching than the fine or suspension. Staus falsely declared to NZGRA or WINZ?

The world now knows all of what i have to say and I will leave it up to them.

Thank you all for My time in this great code.

Where the unemployed,sickness bennys and pensioners can compete with the top trainers in NZ for very little out lay,

I feel better for getting this of my chest,thanks.

[Cockyaleg]

1 hour ago, My Name Is said:

 

Thank you Cockyaleg, You are a school teacher and communicate very well,Im a 4th form drop out, who talks more to dogs than people.Thanks for your kind words for my family ,and Tina says high,or was it why?

 

You are right I do currently work in education, but not as a teacher. More to do with policy. I have never met you, and I have no idea who Tina is. I do know a couple of people in the industry but have no involvement myself. My opinion is based on the transcripts and the statements you have made publically.

I had drinks with a barrister on the weekend, he read the transcripts. His response; every man is innocent until they are not. The charge cannot be beaten. Only the penalty can be mitigated. The evidence and lack of, points overwhelmingly in one direction. The language is at times clumsy. The respondent should not have engaged the public in conversation. That will only create sides and strengthen opposing views. In regard to the penalty, a rap on the knuckles with a ruler. Any future positives to this particular drug should expect the same leniency.

I asked you why information which appeared in the first transcript had since been removed. You have never replied. That information stated that you were a sickness beneficiary who supplement your benefit via racing. Was that information correct or not?

 

[Four shaw]

Thank u my name is.......I’ve learned a lot about ..dermorphin,,,,,,,lthink you have got caught out on the first two positives the second two were thrown in to mask your mistake I no nothing....?  Be honest model citizen no...prove me wrong an I will apologise....your poor mother is on the other channel talking about cameras come on .....just tell her the truth if she doesn’t know ?

[Four shaw]

The evidence is correct 4 positives been using awhile sorry 4yours not mine ????

[aquaman]

As I said earlier in this thread Earl, I believe you. This whole sorry saga does not add up in my mind. You and your parents have been in the game longer than anyone, blemish free, I just cannot believe you would drug your dogs not once, but three times, and all with the same drug, and all in the space of a year. I also find it shameful how all these keyboard warriors are so quick to condemn with their hate and venom. Its a shame how after all these years it has to end up like this. I know the feeling having been shafted myself by an incompetent corrupt bunch of swine that sit in power in Petone. It takes time to adjust to life after racing, but you will, and in a years time you will look back and find you are better off out. You only have to read this thread to see why. All the best John.

[Yankiwi]

At the end of the day, no-one has proof of how the synthetic drug entered the dogs systems on any of the 4 occasions.

On those 4 occasions the drug was in their urine so GRNZ presenting rules have been breached.

The penalty was issued for the first three breaches & then the forth followed soon after.

Apparently, because of this, Earl has given up on the industry which is his right to do.

The synthetic drug turned up from somewhere, so it will be interesting going forward to see if it pops up again & where.

 

Edited July 10, 2019 by Yankiwi

[gambler]

You must have alot of airpoints to oz and back Earl within a short time frame. Was it sardines

[Mehe]

So who would of paid for the trips over there I wonder

[Four shaw]

Great to see the sardine GANG come out to help there BESTIE amass his millions,,,,,,????

[Rockit]

51 minutes ago, Four shaw said:

Great to see the sardine GANG come out to help there BESTIE amass his millions,,,,,,????

Gambler laughs. Weren't you reliant on the same trainer a wee while ago?? 

[Four shaw]

On 7/6/2019 at 6:01 PM, My Name Is said:

Thank you yankiwi,

Earl had 4 dogs test positive for a class 4 (or class 1) substance... Earl's now out of business.

Connect the dots.

It's 3 dogs and which Class is it?. Im now out of business.For no gain.Connect the dots.

Thank you cockyaleg ,

The reason you can not find it in the second transcript, Is we were not allowed to ask how much would you have to give a 25kg bitch for the desired effect, amoungst others Questions. Dermorphin is 40-60 times more powerful than morphine.There are no leaves or readings for this drug. 

 Thank you Mehe, I have said that a few times. 90%  Swabbed Rate. mmm

Me and my family will do a lie detector test, and or anything you can think of.

Rugby's on ,soon.nite

Sitting back on Sunday wondering how you got on with your lie detector test earl ??? ????